Nootropic Agents Enhance the Recruitment of Fast GABAA Inhibition in Rat Neocortex
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چکیده
منابع مشابه
Nootropic agents enhance the recruitment of fast GABAA inhibition in rat neocortex.
It is widely believed that nootropic (cognition-enhancing) agents produce their therapeutic effects by augmenting excitatory synaptic transmission in cortical circuits, primarily through positive modulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionate receptors (AMPARs). However, GABA-mediated inhibition is also critical for cognition, and enhanced GABA function may be likewise ther...
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ژورنال
عنوان ژورنال: Cerebral Cortex
سال: 2004
ISSN: 1460-2199,1047-3211
DOI: 10.1093/cercor/bhh191